99.99% available ASP.NET and SQL Server Architecture

I'll summarise a very nice article here:
Architecture
  • Always use public firewall and:
    • only expose 80, 443 ports;
    • do not open FTP;
    • do not open file sharing ports;
  • Use two Ethernet ports: one for to serve external requests, one for local access.
  • "Keep your load balancer dead simple – use basic round robin".
  • Each router and firewall has a standby one.
  • Get moderately powerful Web servers with enough storage.
  • Run 64bit version of Windows.
  • The whole internal network is fully 1Gbit (network cables, routers/switches, NICs etc).
  • Only use VPN to access your server.
  • Database servers must be the most powerful (RAID 10 Disks, Memory, CPU).
  • Store Database files on a separate physical disk.
  • Always perform backup and log shipping to different physical disks, preferably on RAID 1.
  • Use Windows Clustering for high availability with Storage Area Network.
  • RAM, lots of RAM for Database servers (2 GB + 60% of MDF size).
  • Get Dual Path Fiber Channel connection to SAN from your servers.
  • Have a separate server for moving IIS logs from webserver.
  • Have a large detachable external storage like External USB drives.
  • Use fast SCSI RAID 1 disks.
  • Use separate NIC on all servers that is connected to a separate private network via separate switch for bulk operations.
Please keep in mind these suggestions are for really heavy duty web applications.